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The Formedix Clinic > Datasets

How to Describe Multiple Origins for a Value in Define-XML 2

26 April 2018
by Kevin Burges About The Author

There are many common questions people have when creating Define-XML metadata for their datasets. One of these revolves around how to handle data that can come from multiple sources, such as a CRF or eDT. In the simple case you just create a Value List, and specify the Origin on each Value instead of on the Variable.

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Standardized data - The industry is struggling

2 October 2017
by Kevin Burges About The Author

With FDA now regulating for all new studies to use CDISC standards when submitting data, it's vital that our processes are up to date with the latest standards and fit for purpose.

An FDA presentation at the recent PhUSE Computational Science Symposium tried to shed some light on how we're doing as an industry. It analysed all eCTD submissions from January-February 2017 that used standardized data.

You might be surprised how the submissions fared...

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Homegrown Define-XML vs. Automated Define-XML

23 September 2015
by Ed Chappell About The Author

During the SDTM dataset extraction process, some SAS programmers create the SDTM or ADaM Define-XML directly from the dataset metadata used in the SAS file. This has the perceived advantage of automating the Define-XML creation, but it has a fundamental weakness.

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